Toxicological Effects of Silver Nanoparticles (Ag-NPs) on Different Physiological Parameters of Tadpoles, Polypedates maculatus

Authors

  • R. Pattanayak Dept. of Zoology, College of Basic Science and Humanities, Orissa University of Agriculture and Technology, Bhubaneswar, Odisha (751 003), India
  • Rakesh Das ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, Odisha (751 002), India
  • A. Das ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, Odisha (751 002), India
  • S. K. Padhi ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, Odisha (751 002), India
  • S. S. Sahu Dept. of Zoology, College of Basic Science and Humanities, Orissa University of Agriculture and Technology, Bhubaneswar, Odisha (751 003), India
  • S. Pattnaik Dept. of Zoology, College of Basic Science and Humanities, Orissa University of Agriculture and Technology, Bhubaneswar, Odisha (751 003), India
  • C. S. K. Mishra Dept. of Zoology, College of Basic Science and Humanities, Orissa University of Agriculture and Technology, Bhubaneswar, Odisha (751 003), India
  • S. S. Mishra ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, Odisha (751 002), India
  • C. S. Mohanty CSIR-National Botanical Research Institute, Rana Pratap Marg, Lucknow, Uttar Pradesh (226 001), India
  • G. Sinam CSIR-National Botanical Research Institute, Rana Pratap Marg, Lucknow, Uttar Pradesh (226 001), India
  • H. K. Barman ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, Odisha (751 002), India
  • J. K. Sundaray ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, Odisha (751 002), India
  • P. Swain ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, Odisha (751 002), India

Keywords:

Ag-NPs, growth, metamorphosis, immunity, enzyme profile, Polypedates maculatus

Abstract

The effects of silver nanoparticles (Ag-NPs) on the growth, metamorphosis, innate immune parameters and enzyme profiles of tadpole, Polypedates maculatus were studied. Chronic exposure to Ag-NPs for 60 days at 1 mg l-1 and 5 mg l-1 concentrations caused 10% and 50% mortalities respectively alongwith slow growth and delayed metamorphosis as compared to 0.1 mg l-1 treatment and control (0 mg l-1). The non-specific immune parameters and certain enzyme activities like alkaline phosphatase (ALP), superoxide dismutase (SOD) and lactate dehydrogenase (LDH) varied significantly in a dose dependent manner. The accumulation of silver in the tadpole tissues of treated groups ranged from 0.0966±0.0025 µg g-1 to 0.4718±0.0126 µg g-1 as compared to tissues in control group (0.0758±0.0019 µg g-1). Hence Ag-NPs had significant detrimental effects on growth and other associated physiological parameters of tadpole, Polypedates maculatus when administered at higher concentrations (>1 mg l-1) for longer durations. Thus the toxicity studies of Ag-NPs have to be conducted on wider ranges of target and non-target species to assess their environmental impacts. Furthermore, these results suggest that silver nanoparticles induce a dose-dependent toxicity in physiological parameters of tadpoles, which hinders normal development.This study was aimed to enhance our insight on the health and environmental impact of silver nanoparticles. This study pointed out the adverse effects of Ag-NPs in tadpole species and all applications involving silver nanoparticles should be given special attention and promoted only after detailed studies.

Downloads

Download data is not yet available.

Downloads

Published

2018-10-31

How to Cite

1.
Pattanayak R, Das R, Das A, Padhi SK, Sahu SS, Pattnaik S, et al. Toxicological Effects of Silver Nanoparticles (Ag-NPs) on Different Physiological Parameters of Tadpoles, Polypedates maculatus. IJBSM [Internet]. 2018 Oct. 31 [cited 2025 Sep. 6];9(Oct, 5):647-54. Available from: https://ojs.pphouse.org/index.php/IJBSM/article/view/3763

Issue

Vol. 9 No. Oct, 5 (2018)

Section

Articles

License

Authors retain copyright. Articles published are made available as open access articles, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited. Creative Commons License

This journal permits and encourages authors to share their submitted versions (preprints), accepted versions (postprints) and/or published versions (publisher versions) freely under the CC BY-NC-SA 4.0 license while providing bibliographic details that credit, if applicable.